CABIN1 antibody (Internal Region)

Catalog No. ABIN6260386

The Rabbit Polyclonal anti-CABIN1 antibody (ABIN6260386) specifically detects CABIN1 in WB, IHC, ICC and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for CABIN1 antibody (Internal Region) (ABIN6260386)

Target: CABIN1 (Calcineurin Binding Protein 1 (CABIN1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CABIN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-CABIN1 Antibody

Binding Specificity: Internal Region

Purpose: CABIN1 Antibody

Specificity: CABIN1 Antibody detects endogenous levels of total CABIN1.

Predicted Reactivity: Pig,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CABIN1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200 IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CABIN1

Target: CABIN1 (Calcineurin Binding Protein 1 (CABIN1))

Alternative Name: CABIN1

Background:

Description: May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes.

Gene: CABIN1

Molecular Weight: 246kDa

Gene ID: 23523

UniProt: Q9Y6J0