CEP72 antibody (Internal Region)

Catalog No. ABIN6260771

This Rabbit Polyclonal antibody specifically detects CEP72 in WB, IHC, IF and ICC. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for CEP72 antibody (Internal Region) (ABIN6260771)

Target: CEP72 (Centrosomal Protein 72kDa (CEP72))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP72 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-CEP72 Antibody

Binding Specificity: Internal Region

Purpose: CEP72 Antibody

Specificity: CEP72 Antibody detects endogenous levels of total CEP72

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CEP72, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200 IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CEP72

Target: CEP72 (Centrosomal Protein 72kDa (CEP72))

Alternative Name: CEP72

Background:

Description: Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) (PubMed:19536135). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:26297806).

Gene: CEP72

Molecular Weight: 72 kDa

Gene ID: 55722

UniProt: Q9P209

Pathways: M Phase