CHD6 antibody (C-Term)

Catalog No. ABIN6260797

This anti-CHD6 antibody is a Rabbit Polyclonal antibody detecting CHD6 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for CHD6 antibody (C-Term) (ABIN6260797)

Target: CHD6 (Chromodomain Helicase DNA Binding Protein 6 (CHD6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CHD6 Antibody

Binding Specificity: C-Term

Specificity: CHD6 Antibody detects endogenous levels of total CHD6.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CHD6, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CHD6

Target: CHD6 (Chromodomain Helicase DNA Binding Protein 6 (CHD6))

Alternative Name: CHD6

Background:

Description: DNA-dependent ATPase that plays a role in chromatin remodeling. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin (PubMed:28533432). Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2.

Gene: CHD6

Molecular Weight: 305kDa

Gene ID: 84181

UniProt: Q8TD26

Pathways: Chromatin Binding