CHD6 antibody

Catalog No. ABIN7227878

The Rabbit Polyclonal anti-CHD6 antibody (ABIN7227878) specifically detects CHD6 in IF and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CHD6 antibody (ABIN7227878)

Target: CHD6 (Chromodomain Helicase DNA Binding Protein 6 (CHD6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD6 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-CHD6 Antibody

Purpose: Rabbit Anti-CHD6 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CHD6 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CHD6 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHD6

Target: CHD6 (Chromodomain Helicase DNA Binding Protein 6 (CHD6))

Alternative Name: CHD6

Background: Chromodomain-helicase-DNA-binding protein 6, CHD-6, ATP-dependent helicase CHD6, Radiation-induced gene B proteinCHD6 (Chromodomain Helicase DNA Binding Protein 6) is a Protein Coding gene. Diseases associated with CHD6 include Pitt-Hopkins Syndrome and Developmental Coordination Disorder. CHD6 encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication.

Molecular Weight: 298kD

Gene ID: 84181

UniProt: Q8TD26

Pathways: Chromatin Binding