Claudin 3 antibody (C-Term)

Catalog No. ABIN6260865

The Rabbit Polyclonal anti-Claudin 3 antibody has been validated for WB, IHC, ELISA, IF and ICC. It is suitable to detect Claudin 3 in samples from Human, Mouse and Rat. There is 1 publication available.

Quick Overview for Claudin 3 antibody (C-Term) (ABIN6260865)

Target: Claudin 3 (CLDN3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Claudin 3 Antibody

Binding Specificity: C-Term

Specificity: Claudin 3 Antibody detects endogenous levels of total Claudin 3.

Predicted Reactivity: Pig,Bovine,Sheep,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Claudin 3, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

References for anti-Claudin 3 antibody (ABIN6260865)

Ai, Zhang, Gao, Qin, Zhong, Gu, Li, Qiao, Tian, Cui, Yang, Bi, Xiao, Chen, Liu, Zhou, Sun, Yang: "Sesquiterpene binding Gly-Leu-Ser/Lys-"co-adaptation pocket" to inhibit lung cancer cell epithelial-mesenchymal transition." in: Oncotarget, Vol. 8, Issue 41, pp. 70192-70203, (2018) (PubMed).

Target Details for Claudin 3

Target: Claudin 3 (CLDN3)

Alternative Name: CLDN3

Background:

Description: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Gene: CLDN3

Molecular Weight: 25kDa

Gene ID: 1365

UniProt: O15551

Pathways: Hepatitis C