CPLX2 antibody (Internal Region)

Catalog No. ABIN6261004

Product Details anti-CPLX2 Antibody

Target: CPLX2 (Complexin 2 (CPLX2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPLX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: CPLX2 Antibody detects endogenous levels of total CPLX2.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CPLX2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CPLX2

Target: CPLX2 (Complexin 2 (CPLX2))

Alternative Name: CPLX2 (CPLX2 Products)

Synonyms: 921-L antibody, CPX-2 antibody, CPX2 antibody, Hfb1 antibody, AI413745 antibody, AW492120 antibody, MGC68923 antibody, MGC79539 antibody, complexin 2 antibody, complexin 2 L homeolog antibody, complexin-2 antibody, CPLX2 antibody, Cplx2 antibody, cplx2.L antibody, cplx2 antibody, LOC750228 antibody

Background:

Description: Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis (By similarity).

Gene: CPLX2

Molecular Weight: 18-20 kDa

Gene ID: 10814

UniProt: Q6PUV4

Pathways: Synaptic Vesicle Exocytosis