CXCR1 antibody (N-Term)

Catalog No. ABIN6261126

The Rabbit Polyclonal anti-CXCR1 antibody has been validated for WB, ELISA, IHC, ICC and IF. It is suitable to detect CXCR1 in samples from Human.

Quick Overview for CXCR1 antibody (N-Term) (ABIN6261126)

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-CXCR1 Antibody

Binding Specificity: N-Term

Specificity: CXCR1 Antibody detects endogenous levels of total CXCR1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CXCR1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Alternative Name: CXCR1

Background:

Description: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

Gene: CXCR1

Molecular Weight: 40 kDa

Gene ID: 3577

UniProt: P25024

Pathways: cAMP Metabolic Process