CXCR1 antibody

Catalog No. ABIN7073465

This Rabbit Polyclonal antibody specifically detects CXCR1 in WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CXCR1 antibody (ABIN7073465)

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CXCR1 Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CXCR1

Application Details

Application Notes: WB (H,M,R) 1: 500-1: 1000, IHC/IF (H,M,R) 1:1000-1:4000/1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Alternative Name: CXCR1

Background: CXCR1 is a chemokine receptor, which is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein-activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. Stimulation of CXCR1 in neutrophils by its primary ligand, Interleukin 8, leads to neutrophil chemotaxis and activation.

Molecular Weight: 45 kDa

Gene ID: 227288

NCBI Accession: NP_839972

UniProt: Q810W6

Pathways: cAMP Metabolic Process