alpha Defensin 1 antibody (Internal Region)

Catalog No. ABIN6261263

This Rabbit Polyclonal antibody specifically detects alpha Defensin 1 in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for alpha Defensin 1 antibody (Internal Region) (ABIN6261263)

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Defensin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-alpha Defensin 1 Antibody

Binding Specificity: Internal Region

Purpose: Defensin alpha1 Antibody

Specificity: Defensin alpha1 Antibody detects endogenous levels of total Defensin alpha1

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Defensin alpha1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for alpha Defensin 1

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Alternative Name: Defensin alpha1

Background:

Description: Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Gene: DEFA1, DEFA1B

Molecular Weight: 10 kDa

Gene ID: 1, 667, 728

UniProt: P59665

Pathways: Cellular Response to Molecule of Bacterial Origin