DYNC1H1 antibody (Internal Region)

Catalog No. ABIN6261391

The Rabbit Polyclonal anti-DYNC1H1 antibody (ABIN6261391) specifically detects DYNC1H1 in WB, ELISA, IHC, IF and ICC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DYNC1H1 antibody (Internal Region) (ABIN6261391)

Target: DYNC1H1 (Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNC1H1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-DYNC1H1 Antibody

Binding Specificity: Internal Region

Specificity: DYNC1H1 Antibody detects endogenous levels of total DYNC1H1.

Predicted Reactivity: Pig,Bovine,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DYNC1H1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DYNC1H1

Target: DYNC1H1 (Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1))

Alternative Name: DYNC1H1

Background:

Description: Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity, the force-producing power stroke is thought to occur on release of ADP. Plays a role in mitotic spindle assembly and metaphase plate congression (PubMed:27462074).

Gene: DYNC1H1

Molecular Weight: 532kDa

Gene ID: 1778

UniProt: Q14204

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization