DYNC1H1 antibody (Internal Region)

Catalog No. ABIN6261391

Product Details anti-DYNC1H1 Antibody

Target: DYNC1H1 (Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNC1H1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: DYNC1H1 Antibody detects endogenous levels of total DYNC1H1.

Predicted Reactivity: Pig,Bovine,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DYNC1H1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DYNC1H1

Target: DYNC1H1 (Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1))

Alternative Name: DYNC1H1 (DYNC1H1 Products)

Synonyms: fk70a07 antibody, wu:fk70a07 antibody, p22 antibody, dhc1 antibody, dncl antibody, dyhc antibody, hl-3 antibody, dhc1a antibody, dnch1 antibody, dnecl antibody, dnchc1 antibody, Dnch1 antibody, Dnchc1 antibody, 9930018I23Rik antibody, AI894280 antibody, DHC1 antibody, DHC1a antibody, DNCL antibody, Dnec1 antibody, Dnecl antibody, Loa antibody, MAP1C antibody, P22 antibody, Swl antibody, mKIAA0325 antibody, DNCH1 antibody, DNECL antibody, DYHC antibody, HL-3 antibody, SMALED1 antibody, dynein, cytoplasmic 1, heavy chain 1 antibody, dynein cytoplasmic 1 heavy chain 1 antibody, dync1h1 antibody, DYNC1H1 antibody, Dync1h1 antibody

Background:

Description: Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity, the force-producing power stroke is thought to occur on release of ADP. Plays a role in mitotic spindle assembly and metaphase plate congression (PubMed:27462074).

Gene: DYNC1H1

Molecular Weight: 532kDa

Gene ID: 1778

UniProt: Q14204

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization