EFNB1/2 (C-Term) antibody

Catalog No. ABIN6261453

The Rabbit Polyclonal anti-EFNB1/2 antibody is suitable to detect EFNB1/2 in samples from Human, Mouse, Rat and Monkey. It has been validated for WB, IHC, ICC and IF.

Quick Overview for EFNB1/2 (C-Term) antibody (ABIN6261453)

Target: EFNB1/2

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details

Binding Specificity: C-Term

Purpose: EFNB1/2 Antibody

Specificity: EFNB1/2 Antibody detects endogenous levels of total EFNB1/2

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human EFNB2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details

Target: EFNB1/2

Background:

Description: Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).

Gene: EFNB1

Molecular Weight: 59kDa

Gene ID: 1947

UniProt: P98172