SLC27A1 antibody (Internal Region)

Catalog No. ABIN6261687

The Rabbit Polyclonal anti-SLC27A1 antibody is suitable to detect SLC27A1 in samples from Human, Rat and Mouse. It has been validated for WB, IF and ICC.

Quick Overview for SLC27A1 antibody (Internal Region) (ABIN6261687)

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC27A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-SLC27A1 Antibody

Binding Specificity: Internal Region

Purpose: FATP1 Antibody

Specificity: FATP1 Antibody detects endogenous levels of total FATP1.

Predicted Reactivity: Bovine,Horse,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FATP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: IF/ICC 1:100-1:500,WB 1:1000-3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SLC27A1

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Alternative Name: FATP1

Background:

Description: Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane (PubMed:28178239). Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism (By similarity).

Gene: SLC27A1

Molecular Weight: 65 kDa

Gene ID: 376497

UniProt: Q6PCB7

Pathways: Inositol Metabolic Process, Regulation of Lipid Metabolism by PPARalpha