ZFPM2 antibody (C-Term)

Catalog No. ABIN6261778

This anti-ZFPM2 antibody is a Rabbit Polyclonal antibody detecting ZFPM2 in WB, ELISA, IHC, ICC and IF. Suitable for Human and Mouse.

Quick Overview for ZFPM2 antibody (C-Term) (ABIN6261778)

Target: ZFPM2 (Zinc Finger Protein, FOG Family Member 2 (ZFPM2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFPM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-ZFPM2 Antibody

Binding Specificity: C-Term

Specificity: FOG2 Antibody detects endogenous levels of total FOG2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FOG2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ZFPM2

Target: ZFPM2 (Zinc Finger Protein, FOG Family Member 2 (ZFPM2))

Alternative Name: ZFPM2

Background:

Description: Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2 (By similarity).

Gene: ZFPM2

Molecular Weight: 128kDa

Gene ID: 23414

UniProt: Q8WW38