FYB antibody

Catalog No. ABIN6261835

This anti-FYB antibody is a Rabbit Polyclonal antibody detecting FYB in WB, ELISA, ICC, IF and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for FYB antibody (ABIN6261835)

Target: FYB (FYN-Binding Protein (FYB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FYB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-FYB Antibody

Specificity: FYB Antibody detects endogenous levels of total FYB

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FYB

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000 IHC 1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for FYB

Target: FYB (FYN-Binding Protein (FYB))

Alternative Name: FYB

Background:

Description: Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.

Gene: FYB1

Molecular Weight: 110 kDa

Gene ID: 2533

UniProt: O15117

Pathways: TCR Signaling, Protein targeting to Nucleus