FYB antibody (AA 620-700)

Catalog No. ABIN7214972

This Rabbit Polyclonal antibody specifically detects FYB in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FYB antibody (AA 620-700) (ABIN7214972)

Target: FYB (FYN-Binding Protein (FYB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FYB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FYB Antibody

Binding Specificity: AA 620-700

Purpose: Rabbit Anti-Fyb Polyclonal Antibody

Specificity: Fyb Polyclonal Antibody detects endogenous levels of Fyb protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Fyb at AA range: 620-700

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FYB

Target: FYB (FYN-Binding Protein (FYB))

Alternative Name: Fyb

Background: FYB, SLAP130, FYN-binding protein, Adhesion and degranulation promoting adaptor protein, ADAP, FYB-120/130, p120/p130, FYN-T-binding protein, SLAP-130, SLP-76-associated phosphoproteinFYN-binding protein encoded by FYB is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. FYN-binding protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 85kD

Gene ID: 2533

UniProt: O15117

Pathways: TCR Signaling, Protein targeting to Nucleus