GDF3 antibody (Internal Region)

Catalog No. ABIN6261928

The Rabbit Polyclonal anti-GDF3 antibody (ABIN6261928) specifically detects GDF3 in WB, IHC, ICC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GDF3 antibody (Internal Region) (ABIN6261928)

Target: GDF3 (Growth Differentiation Factor 3 (GDF3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-GDF3 Antibody

Binding Specificity: Internal Region

Purpose: GDF3 Antibody

Specificity: GDF3 Antibody detects endogenous levels of total GDF3.

Predicted Reactivity: Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GDF3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GDF3

Target: GDF3 (Growth Differentiation Factor 3 (GDF3))

Alternative Name: GDF3

Background:

Description: Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor TDGF1/Cripto (By similarity). Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and TDGF1/Cripto (PubMed:21805089).

Gene: GDF3

Molecular Weight: 41 kDa

Gene ID: 9573

UniProt: Q9NR23