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HIPK1 antibody (N-Term)

HIPK1 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6262240
  • Target See all HIPK1 Antibodies
    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
    Binding Specificity
    • 15
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 53
    • 27
    • 16
    • 15
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 48
    • 5
    Rabbit
    Clonality
    • 49
    • 4
    Polyclonal
    Conjugate
    • 18
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIPK1 antibody is un-conjugated
    Application
    • 40
    • 24
    • 17
    • 13
    • 13
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Specificity
    HIPK1 Antibody detects endogenous levels of total HIPK1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human HIPK1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product HIPK1 Primary Antibody
  • Application Notes
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
    Alternative Name
    HIPK1 (HIPK1 Products)
    Synonyms
    HIPK1 antibody, myak antibody, nbak2 antibody, hipk1 antibody, Myak antibody, Nbak2 antibody, 1110062K04Rik antibody, homeodomain interacting protein kinase 1 antibody, homeodomain interacting protein kinase 1 L homeolog antibody, homeodomain interacting protein kinase 1 S homeolog antibody, HIPK1 antibody, hipk1.L antibody, hipk1 antibody, hipk1.S antibody, Hipk1 antibody
    Background

    Description: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.

    Gene: HIPK1

    Molecular Weight
    131 kDa
    Gene ID
    204851
    UniProt
    Q86Z02
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