Histone H1 antibody (Internal Region)

Catalog No. ABIN6262247

This Rabbit Polyclonal antibody specifically detects Histone H1 in WB, IF and ICC. It exhibits reactivity toward Human and Rat.

Quick Overview for Histone H1 antibody (Internal Region) (ABIN6262247)

Target: Histone H1

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Histone H1 Antibody

Binding Specificity: Internal Region

Purpose: Histone H1 Antibody

Specificity: Histone H1 Antibody detects endogenous levels of total Histone H1.

Predicted Reactivity: Bovine,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Histone H1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Histone H1

Target: Histone H1

Background:

Description: May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity).

Gene: H1FOO

Molecular Weight: 21kDa

Gene ID: 132243

UniProt: Q8IZA3