HIST1H2BH antibody (N-Term)

Catalog No. ABIN6262259

This Rabbit Polyclonal antibody specifically detects HIST1H2BH in WB, ELISA, ICC, IF and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HIST1H2BH antibody (N-Term) (ABIN6262259)

Target: HIST1H2BH (Histone Cluster 1, H2bh (HIST1H2BH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H2BH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-HIST1H2BH Antibody

Binding Specificity: N-Term

Specificity: Histone H2B Antibody detects endogenous levels of total Histone H2B.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Histone H2B, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for HIST1H2BH

Target: HIST1H2BH (Histone Cluster 1, H2bh (HIST1H2BH))

Alternative Name: HIST1H2BH

Background:

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene: HIST1H2BH

Molecular Weight: 13 kDa

Gene ID: 8345

UniProt: Q93079

Pathways: Telomere Maintenance