IL10RB antibody (C-Term)

Catalog No. ABIN6262533

Product Details anti-IL10RB Antibody

Target: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL10RB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: IL10RB Antibody detects endogenous levels of total IL10RB.

Predicted Reactivity: Horse

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IL10RB, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for IL10RB

Target: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Alternative Name: IL10RB (IL10RB Products)

Synonyms: IL10R2 antibody, IL10RB antibody, il10r2 antibody, CDW210B antibody, CRF2-4 antibody, CRFB4 antibody, D21S58 antibody, D21S66 antibody, IL-10R2 antibody, 6620401D04Rik antibody, AI528744 antibody, Crfb4 antibody, D16H21S58 antibody, D21S58h antibody, Il10r2 antibody, RGD1560373 antibody, interleukin 10 receptor subunit beta antibody, interleukin 10 receptor subunit beta S homeolog antibody, interleukin-10 receptor subunit beta antibody, interleukin 10 receptor, beta antibody, IL10RB antibody, il10rb.S antibody, LOC473966 antibody, LOC478404 antibody, il10rb antibody, Il10rb antibody

Background:

Description: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

Gene: IL10RB

Molecular Weight: 37 kDa

Gene ID: 3588

UniProt: Q08334