LARP7 antibody (C-Term)

Catalog No. ABIN6262911

The Rabbit Polyclonal anti-LARP7 antibody is suitable to detect LARP7 in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for LARP7 antibody (C-Term) (ABIN6262911)

Target: LARP7 (La Ribonucleoprotein Domain Family, Member 7 (LARP7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LARP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LARP7 Antibody

Binding Specificity: C-Term

Specificity: LARP7 Antibody detects endogenous levels of total LARP7.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human LARP7, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for LARP7

Target: LARP7 (La Ribonucleoprotein Domain Family, Member 7 (LARP7))

Alternative Name: LARP7

Background:

Description: Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

Gene: LARP7

Molecular Weight: 67 kDa

Gene ID: 51574

UniProt: Q4G0J3

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection