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MECP2 antibody (N-Term)

This anti-MECP2 antibody is a Rabbit Polyclonal antibody detecting MECP2 in WB, ELISA, IF and ICC. Suitable for Human, Mouse and Rat.
Catalog No. ABIN6263185

Quick Overview for MECP2 antibody (N-Term) (ABIN6263185)

Target

See all MECP2 Antibodies
MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Reactivity

  • 110
  • 41
  • 30
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 102
  • 19
  • 1
Rabbit

Clonality

  • 103
  • 19
Polyclonal

Conjugate

  • 81
  • 9
  • 7
  • 7
  • 6
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MECP2 antibody is un-conjugated

Application

  • 92
  • 61
  • 48
  • 26
  • 20
  • 15
  • 11
  • 10
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Binding Specificity

    • 13
    • 11
    • 11
    • 8
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificity

    MeCP2 Antibody detects endogenous levels of total MeCP2.

    Predicted Reactivity

    Horse,Rabbit,Dog

    Purification

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human MeCP2, corresponding to a region within N-terminal amino acids.

    Isotype

    IgG
  • Application Notes

    WB 1:1000-2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C. Stable for 12 months from date of receipt.

    Expiry Date

    12 months
  • Target

    MECP2 (Methyl CpG Binding Protein 2 (MECP2))

    Alternative Name

    MECP2

    Background

    Description: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).

    Gene: MECP2

    Molecular Weight

    53 kDa.

    Gene ID

    4204

    UniProt

    P51608

    Pathways

    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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