MED11 antibody (Internal Region)

Catalog No. ABIN6263188

The Rabbit Polyclonal anti-MED11 antibody (ABIN6263188) specifically detects MED11 in WB, ICC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MED11 antibody (Internal Region) (ABIN6263188)

Target: MED11 (Mediator Complex Subunit 11 (MED11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED11 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-MED11 Antibody

Binding Specificity: Internal Region

Purpose: MED11 Antibody

Specificity: MED11 Antibody detects endogenous levels of total MED11.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MED11, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MED11

Target: MED11 (Mediator Complex Subunit 11 (MED11))

Alternative Name: MED11

Background:

Description: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gene: MED11

Molecular Weight: 13 kDa

Gene ID: 400569

UniProt: Q9P086

Pathways: Regulation of Lipid Metabolism by PPARalpha