MGLL antibody (N-Term)

Catalog No. ABIN6263238

The Rabbit Polyclonal anti-MGLL antibody has been validated for WB, IHC and ELISA. It is suitable to detect MGLL in samples from Human, Rat and Mouse.

Quick Overview for MGLL antibody (N-Term) (ABIN6263238)

Target: MGLL (Monoglyceride Lipase (MGLL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGLL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-MGLL Antibody

Binding Specificity: N-Term

Specificity: MGLL Antibody detects endogenous levels of total MGLL.

Predicted Reactivity: Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MGLL, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MGLL

Target: MGLL (Monoglyceride Lipase (MGLL))

Alternative Name: MGLL

Background:

Description: Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (PubMed:20079333).

Gene: MGLL

Molecular Weight: 33 kDa

Gene ID: 11343

UniProt: Q99685

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Lipid Metabolism