C18orf8 antibody (C-Term)

Catalog No. ABIN6263249

This Rabbit Polyclonal antibody specifically detects C18orf8 in WB, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for C18orf8 antibody (C-Term) (ABIN6263249)

Target: C18orf8 (Chromosome 18 Open Reading Frame 8 (C18orf8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C18orf8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-C18orf8 Antibody

Binding Specificity: C-Term

Purpose: MIC1 Antibody

Specificity: MIC1 Antibody detects endogenous levels of total MIC1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MIC1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for C18orf8

Target: C18orf8 (Chromosome 18 Open Reading Frame 8 (C18orf8))

Alternative Name: MIC1

Background:

Description: Componement of the CCZ1-MON1 RAB7A guanine exchange factor (GEF). Acts as a positive regulator of CCZ1-MON1A/B function necessary for endosomal/autophagic flux and efficient RAB7A localization (PubMed:29038162).

Gene: C18orf8

Molecular Weight: 74 kDa

Gene ID: 29919

UniProt: Q96DM3