TMEM67 antibody (Internal Region)

Catalog No. ABIN6263272

Product Details anti-TMEM67 Antibody

Target: TMEM67 (Transmembrane Protein 67 (TMEM67))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM67 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: MKS3 Antibody detects endogenous levels of total MKS3.

Predicted Reactivity: Pig,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MKS3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TMEM67

Target: TMEM67 (Transmembrane Protein 67 (TMEM67))

Alternative Name: TMEM67 (TMEM67 Products)

Synonyms: JBTS6 antibody, MECKELIN antibody, MKS3 antibody, NPHP11 antibody, TNEM67 antibody, 5330408M12Rik antibody, B230117O07 antibody, b2b1163.1Clo antibody, b2b1291.1Clo antibody, Wpk antibody, transmembrane protein 67 antibody, TMEM67 antibody, tmem67 antibody, Tmem67 antibody

Background:

Description: Required for ciliary structure and function. Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Involved in centrosome migration to the apical cell surface during early ciliogenesis. Involved in the regulation of cilia length and appropriate number through the control of centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (SFTPC).

Gene: TMEM67

Molecular Weight: 112kDa

Gene ID: 91147

UniProt: Q5HYA8