MLKL antibody (Internal Region)
(1 reference)-
- Target See all MLKL Antibodies
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MLKL antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- MLKL Antibody detects endogenous levels of total MLKL.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MLKL, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MLKL Primary Antibody
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anti-Mixed Lineage Kinase Domain-Like (MLKL) antibody
MLKL Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-471) antibodyMLKL Reactivity: Human WB, ELISA, IHC (p), IF Host: Mouse Monoclonal 3B2 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472) antibodyMLKL Reactivity: Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) antibodyMLKL Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (C-Term) antibodyMLKL Reactivity: Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (pSer358) antibodyMLKL Reactivity: Human IHC (p) Host: Mouse Monoclonal 6E3 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-472) antibodyMLKL Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Mouse Monoclonal 3B2 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL Reactivity: Mouse WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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: "Alterations in necroptosis during ALDH2‑mediated protection against high glucose‑induced H9c2 cardiac cell injury." in: Molecular medicine reports, Vol. 18, Issue 3, pp. 2807-2815, (2018) (PubMed).
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: "Alterations in necroptosis during ALDH2‑mediated protection against high glucose‑induced H9c2 cardiac cell injury." in: Molecular medicine reports, Vol. 18, Issue 3, pp. 2807-2815, (2018) (PubMed).
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- Target
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
- Alternative Name
- MLKL (MLKL Products)
- Synonyms
- MLKL antibody, 9130019I15Rik antibody, mixed lineage kinase domain like pseudokinase antibody, mixed lineage kinase domain-like antibody, MLKL antibody, mlkl antibody, Mlkl antibody
- Background
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Description: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Gene: MLKL
- Molecular Weight
- 54kDa
- Gene ID
- 197259
- UniProt
- Q8NB16
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