NDUFA13 antibody (N-Term)

Catalog No. ABIN6263558

Product Details anti-NDUFA13 Antibody

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFA13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: NDUFA13 Antibody detects endogenous levels of total NDUFA13.

Predicted Reactivity: Pig,Zebrafish,Bovine,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NDUFA13, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Alternative Name: NDUFA13 (NDUFA13 Products)

Synonyms: GRIM-19 antibody, Ndufa13 antibody, B16.6 antibody, CDA016 antibody, GRIM19 antibody, 2700054G14Rik antibody, AU022060 antibody, CGI-39 antibody, Grim19 antibody, RGD1565358 antibody, YJEFN3 antibody, NADH:ubiquinone oxidoreductase subunit A13 antibody, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 antibody, cell death-regulatory protein GRIM19 antibody, GRIM-19 protein antibody, NADH:ubiquinone oxidoreductase subunit A13 L homeolog antibody, ndufa13 antibody, LOC655421 antibody, Ndufa13 antibody, CpipJ_CPIJ000908 antibody, Bm1_18845 antibody, ndufa13.L antibody, NDUFA13 antibody

Background:

Description: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis (PubMed:27626371). Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:27626371). Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes (PubMed:15753091).

Gene: NDUFA13

Molecular Weight: 17kDa

Gene ID: 51079

UniProt: Q9P0J0

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling