PDE1A antibody (Internal Region)

Catalog No. ABIN6264086

This Rabbit Polyclonal antibody specifically detects PDE1A in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PDE1A antibody (Internal Region) (ABIN6264086)

Target: PDE1A (Phosphodiesterase 1A (PDE1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PDE1A Antibody

Binding Specificity: Internal Region

Specificity: PDE1A Antibody detects endogenous levels of total PDE1A.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PDE1A, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PDE1A

Target: PDE1A (Phosphodiesterase 1A (PDE1A))

Alternative Name: PDE1A

Background:

Description: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.

Gene: PDE1A

Molecular Weight: 61 kDa

Gene ID: 5136

UniProt: P54750

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma