PDE2A antibody (C-Term)

Catalog No. ABIN6264089

This Rabbit Polyclonal antibody specifically detects PDE2A in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PDE2A antibody (C-Term) (ABIN6264089)

Target: PDE2A (phosphodiesterase 2A, CGMP-Stimulated (PDE2A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE2A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PDE2A Antibody

Binding Specificity: C-Term

Specificity: PDE2A Antibody detects endogenous levels of total PDE2A.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PDE2A, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PDE2A

Target: PDE2A (phosphodiesterase 2A, CGMP-Stimulated (PDE2A))

Alternative Name: PDE2A

Background:

Description: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line) (PubMed:24705027).

Gene: PDE2A

Molecular Weight: 106 kDa

Gene ID: 5138

UniProt: O00408

Pathways: cAMP Metabolic Process, Synaptic Membrane