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PDE5A antibody (C-Term)

This anti-PDE5A antibody is a Rabbit Polyclonal antibody detecting PDE5A in WB and ELISA. Suitable for Human, Rat and Mouse.
Catalog No. ABIN6264094

Quick Overview for PDE5A antibody (C-Term) (ABIN6264094)

Target

See all PDE5A Antibodies
PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Reactivity

  • 28
  • 8
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Rat, Mouse

Host

  • 23
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  • 1
Rabbit

Clonality

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Polyclonal

Conjugate

  • 18
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PDE5A antibody is un-conjugated

Application

  • 21
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  • 4
  • 2
  • 2
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  • 1
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  • 1
Western Blotting (WB), ELISA
  • Binding Specificity

    • 5
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 1
    • 1
    C-Term

    Specificity

    PDE5A Antibody detects endogenous levels of total PDE5A.

    Predicted Reactivity

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    Purification

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human PDE5A, corresponding to a region within C-terminal amino acids.

    Isotype

    IgG
  • Application Notes

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C. Stable for 12 months from date of receipt.

    Expiry Date

    12 months
  • Target

    PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

    Alternative Name

    PDE5A

    Background

    Description: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide-generated cGMP (PubMed:15489334).

    Gene: PDE5A

    Molecular Weight

    100 kDa

    Gene ID

    8654

    UniProt

    O76074

    Pathways

    Regulation of G-Protein Coupled Receptor Protein Signaling
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