P4HB antibody (C-Term)

Catalog No. ABIN6264112

The Rabbit Polyclonal anti-P4HB antibody (ABIN6264112) specifically detects P4HB in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for P4HB antibody (C-Term) (ABIN6264112)

Target: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P4HB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-P4HB Antibody

Binding Specificity: C-Term

Purpose: PDI Antibody

Specificity: PDI Antibody detects endogenous levels of total PDI.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PDI, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for P4HB

Target: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Alternative Name: PDI

Background:

Description: Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.

Gene: PDIA2

Molecular Weight: 61 kDa

Gene ID: 64714

UniProt: Q13087

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism