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POLR2D antibody (N-Term)

POLR2D Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264344
  • Target See all POLR2D Antibodies
    POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 6
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 31
    • 3
    Rabbit
    Clonality
    • 32
    • 2
    Polyclonal
    Conjugate
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLR2D antibody is un-conjugated
    Application
    • 22
    • 20
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    POLR2D Antibody detects endogenous levels of total POLR2D.
    Predicted Reactivity
    Pig,Bovine,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human POLR2D, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product POLR2D Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))
    Alternative Name
    POLR2D (POLR2D Products)
    Synonyms
    wu:fa95b11 antibody, zgc:110435 antibody, HSRBP4 antibody, HSRPB4 antibody, RBP4 antibody, RPB16 antibody, 2310002G05Rik antibody, 2610028L19Rik antibody, RNA polymerase II subunit D antibody, DNA-directed RNA polymerase II 16 kDa polypeptide antibody, polymerase (RNA) II (DNA directed) polypeptide D antibody, Polr2d antibody, CpipJ_CPIJ006734 antibody, UREG_01395 antibody, LOC100282338 antibody, polr2d antibody, POLR2D antibody
    Background

    Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity).

    Gene: POLR2D

    Molecular Weight
    16kDa
    Gene ID
    5433
    UniProt
    O15514
    Pathways
    Regulatory RNA Pathways
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