RAB14 antibody (C-Term)

Catalog No. ABIN6264557

This Rabbit Polyclonal antibody specifically detects RAB14 in WB, IHC, IF and ICC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for RAB14 antibody (C-Term) (ABIN6264557)

Target: RAB14 (RAB14, Member RAS Oncogene Family (RAB14))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-RAB14 Antibody

Binding Specificity: C-Term

Specificity: RAB14 Antibody detects endogenous levels of total RAB14.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RAB14, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for RAB14

Target: RAB14 (RAB14, Member RAS Oncogene Family (RAB14))

Alternative Name: RAB14

Background:

Description: Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.

Gene: RAB14

Molecular Weight: 24 kDa

Gene ID: 51552

UniProt: P61106

Pathways: Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome