RAB8B antibody (C-Term)

Catalog No. ABIN6264592

This anti-RAB8B antibody is a Rabbit Polyclonal antibody detecting RAB8B in ELISA, WB and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for RAB8B antibody (C-Term) (ABIN6264592)

Target: RAB8B (RAB8B, Member RAS Oncogene Family (RAB8B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB8B antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RAB8B Antibody

Binding Specificity: C-Term

Specificity: RAB8B Antibody detects endogenous levels of total RAB8B.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RAB8B, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for RAB8B

Target: RAB8B (RAB8B, Member RAS Oncogene Family (RAB8B))

Alternative Name: RAB8B

Background:

Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells (By similarity).

Gene: RAB8B

Molecular Weight: 24 kDa

Gene ID: 51762

UniProt: Q92930

Pathways: Positive Regulation of Peptide Hormone Secretion, Cell-Cell Junction Organization