RRAGD antibody (Internal Region)

Catalog No. ABIN6264864

The Rabbit Polyclonal anti-RRAGD antibody is suitable to detect RRAGD in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for RRAGD antibody (Internal Region) (ABIN6264864)

Target: RRAGD (Ras-Related GTP Binding D (RRAGD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRAGD antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RRAGD Antibody

Binding Specificity: Internal Region

Specificity: RRAGD Antibody detects endogenous levels of total RRAGD.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RRAGD, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for RRAGD

Target: RRAGD (Ras-Related GTP Binding D (RRAGD))

Alternative Name: RRAGD

Background:

Description: Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.

Gene: RRAGD

Molecular Weight: 46 kDa

Gene ID: 58528

UniProt: Q9NQL2