FRZB antibody (C-Term)

Catalog No. ABIN6265028

This Rabbit Polyclonal antibody specifically detects FRZB in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FRZB antibody (C-Term) (ABIN6265028)

Target: FRZB (Frizzled-Related Protein (FRZB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRZB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FRZB Antibody

Binding Specificity: C-Term

Specificity: SFRP3 Antibody detects endogenous levels of total SFRP3.

Predicted Reactivity: Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SFRP3, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for FRZB

Target: FRZB (Frizzled-Related Protein (FRZB))

Alternative Name: FRZB

Background:

Description: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

Gene: FRZB

Molecular Weight: 36 kDa

Gene ID: 2487

UniProt: Q92765

Pathways: WNT Signaling, Positive Regulation of fat Cell Differentiation