FRZB antibody (AA 166-325)

Catalog No. ABIN7168685

Product Details anti-FRZB Antibody

Target: FRZB (Frizzled-Related Protein (FRZB))

Binding Specificity: AA 166-325

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRZB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Secreted frizzled-related protein 3 protein (166-325AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FRZB

Target: FRZB (Frizzled-Related Protein (FRZB))

Alternative Name: FRZB (FRZB Products)

Synonyms: Frp antibody, Sfrp3 antibody, frezzled antibody, fritz antibody, frzb-1 antibody, FRE antibody, FRITZ antibody, FRP-3 antibody, FRZB-1 antibody, FRZB-PEN antibody, FRZB1 antibody, FZRB antibody, OS1 antibody, SFRP3 antibody, SRFP3 antibody, hFIZ antibody, Frzb-1 antibody, frizzled-related protein antibody, Frzb antibody, FRZB antibody

Background:

Background: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

Aliases: FRZB antibody, FIZ antibody, FRE antibody, FRP antibody, FRZB1 antibody, SFRP3 antibody, Secreted frizzled-related protein 3 antibody, sFRP-3 antibody, Frezzled antibody, Fritz antibody, Frizzled-related protein 1 antibody, FrzB-1 antibody

UniProt: Q92765

Pathways: WNT Signaling, Positive Regulation of fat Cell Differentiation