beta Synuclein antibody (C-Term)

Catalog No. ABIN6265408

Product Details anti-beta Synuclein Antibody

Target: beta Synuclein (SNCB) (Synuclein, beta (SNCB))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Synuclein antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Synuclein beta Antibody detects endogenous levels of total Synuclein beta.

Predicted Reactivity: Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Synuclein beta, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for beta Synuclein

Target: beta Synuclein (SNCB) (Synuclein, beta (SNCB))

Alternative Name: SNCB (SNCB Products)

Synonyms: AI838531 antibody, betaSYN antibody, zgc:66343 antibody, sncb antibody, MGC75784 antibody, LOC619281 antibody, SNCB antibody, syub antibody, synuclein beta antibody, synuclein, beta antibody, synuclein beta L homeolog antibody, Beta-synuclein antibody, SNCB antibody, Sncb antibody, sncb antibody, sncb.L antibody, syub antibody

Background:

Description: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

Gene: SNCB

Molecular Weight: 14 kDa

Gene ID: 6620

UniProt: Q16143