Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody

Details for Product No. ABIN6265513
Target
Reactivity
Human, Mouse, Rat
93
32
22
Host
Rabbit
67
22
7
2
Clonality
Polyclonal
Conjugate
Un-conjugated
11
10
10
5
4
4
3
2
2
2
2
2
2
2
2
2
2
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
49
40
34
26
9
4
4
4
2
2
1
Options
Immunogen A synthesized peptide derived from human TDGF1
Isotype IgG
Specificity TDGF1 Antibody detects endogenous levels of total TDGF1
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Target
Alternative Name TDGF1 (TDGF1 Antibody Abstract)
Background

Description: GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714). Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953).

Gene: TDGF1

Molecular Weight 21kDa
Gene ID 6997
UniProt P13385
Pathways EGFR Signaling Pathway
Application Notes WB 1:500-1:2000 IHC 1:50-1:200
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months
Images
Image no. 1 for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (ABIN6265513) Western blot analysis of NCCIT lysate using TDGF1 antibody. The lane on the left is ...
Image no. 2 for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (ABIN6265513) ABIN6276479 at 1/100 staining Human lung tissue by IHC-P. The sample was formaldehyde...