TDGF1 antibody (AA 32-150) (HRP)

Catalog No. ABIN7171774

Product Details anti-TDGF1 Antibody (HRP)

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Binding Specificity: AA 32-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDGF1 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Teratocarcinoma-derived growth factor 1 protein (32-150AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TDGF1

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Alternative Name: TDGF1 (TDGF1 Products)

Synonyms: CR antibody, CRGF antibody, CRIPTO antibody, CR1 antibody, cripto antibody, cb85 antibody, tdgf1 antibody, wu:fe01d04 antibody, zgc:109829 antibody, Cripto-1 antibody, cr1 antibody, cr1a antibody, frl-1 antibody, frl1 antibody, xcr1 antibody, TDGF1 antibody, tdgf3 antibody, cripto-3 antibody, teratocarcinoma-derived growth factor 1 antibody, teratocarcinoma-derived growth factor 1, member 3 L homeolog antibody, teratocarcinoma-derived growth factor 1, member 1 antibody, TDGF1 antibody, Tdgf1 antibody, tdgf1 antibody, tdgf1.3.L antibody, tdgf1.1 antibody

Background:

Background: GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714). Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953).

Aliases: CR antibody, CRGF antibody, Cripto 1 antibody, Cripto 1 growth factor antibody, cripto antibody, Cripto-1 growth factor antibody, Cripto1 growth factor antibody, Epidermal growth factor like cripto protein CR1 antibody, Epidermal growth factor-like cripto protein CR1 antibody, TDGF 1 antibody, TDGF1 antibody, TDGF1_HUMAN antibody, Teratocarcinoma derived growth factor 1 antibody, Teratocarcinoma-derived growth factor 1 antibody

UniProt: P13385

Pathways: EGFR Signaling Pathway