DP1 antibody (C-Term)

Catalog No. ABIN6265535

This Rabbit Polyclonal antibody specifically detects DP1 in WB, IHC, ELISA, IF and ICC. It exhibits reactivity toward Human and Rat.

Quick Overview for DP1 antibody (C-Term) (ABIN6265535)

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-DP1 Antibody

Binding Specificity: C-Term

Specificity: TFDP1 Antibody detects endogenous levels of total TFDP1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TFDP1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DP1

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Alternative Name: TFDP1

Background:

Description: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication (PubMed:8405995, PubMed:7739537). The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812).

Gene: TFDP1

Molecular Weight: 55kDa

Gene ID: 7027

UniProt: Q14186

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases