Protein Tob1 (TOB1) (Internal Region) antibody

Catalog No. ABIN6265667

This Rabbit Polyclonal antibody specifically detects Protein Tob1 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for Protein Tob1 (TOB1) (Internal Region) antibody (ABIN6265667)

Target: Protein Tob1 (TOB1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details

Binding Specificity: Internal Region

Specificity: TOB1 Antibody detects endogenous levels of total TOB1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TOB1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details

Target: Protein Tob1 (TOB1)

Alternative Name: TOB1

Background:

Description: Anti-proliferative protein, the function is mediated by association with deadenylase subunits of the CCR4-NOT complex (PubMed:8632892, PubMed:23236473). Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay (PubMed:21336257).

Gene: TOB1

Molecular Weight: 40kDa

Gene ID: 10140

UniProt: P50616