UGGT1 antibody (N-Term)

Catalog No. ABIN6265874

This Rabbit Polyclonal antibody specifically detects UGGT1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for UGGT1 antibody (N-Term) (ABIN6265874)

Target: UGGT1 (UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGGT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-UGGT1 Antibody

Binding Specificity: N-Term

Purpose: UGGT1 Antibody

Specificity: UGGT1 Antibody detects endogenous levels of total UGGT1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human UGGT1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for UGGT1

Target: UGGT1 (UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1))

Alternative Name: UGGT1

Background:

Description: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.

Gene: UGGT1

Molecular Weight: 177 kDa

Gene ID: 56886

UniProt: Q9NYU2

Pathways: Activation of Innate immune Response