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USP9X antibody (N-Term)

USP9X Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265937
  • Target See all USP9X Antibodies
    USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))
    Binding Specificity
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 47
    • 33
    • 29
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 40
    • 5
    • 2
    Rabbit
    Clonality
    • 35
    • 12
    Polyclonal
    Conjugate
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP9X antibody is un-conjugated
    Application
    • 32
    • 14
    • 10
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    USP9X Antibody detects endogenous levels of total USP9X.
    Predicted Reactivity
    Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human USP9X, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product USP9X Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))
    Alternative Name
    USP9X (USP9X Products)
    Synonyms
    DFFRX antibody, FAF antibody, FAM antibody, RGD1560056 antibody, faf antibody, fam antibody, dffrx antibody, 5730589N07Rik antibody, AA407302 antibody, AA407699 antibody, AL022658 antibody, AL022749 antibody, Dffrx antibody, FAF-X antibody, Fafl antibody, ubiquitin specific peptidase 9, X-linked antibody, ubiquitin specific peptidase 9, X chromosome antibody, USP9X antibody, Usp9x antibody, usp9x antibody
    Background

    Description: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes 'Lys-48'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinates alkylation repair enzyme ALKBH3. OTUD4 recruits USP7 and USP9X to stabilize ALKBH3, thereby promoting the repair of alkylated DNA lesions (PubMed:25944111). Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Involved in axonal growth and neuronal cell migration (PubMed:16322459, PubMed:18254724, PubMed:19135894, PubMed:24607389).

    Gene: USP9X

    Molecular Weight
    260-290 kDa
    Gene ID
    8239
    UniProt
    Q93008
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