WARS antibody (Internal Region)

Catalog No. ABIN6266008

The Rabbit Polyclonal anti-WARS antibody (ABIN6266008) specifically detects WARS in WB, IHC, ICC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for WARS antibody (Internal Region) (ABIN6266008)

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WARS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-WARS Antibody

Binding Specificity: Internal Region

Purpose: WARS Antibody

Specificity: WARS Antibody detects endogenous levels of total WARS.

Predicted Reactivity: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WARS, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for WARS

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Alternative Name: WARS

Background:

Description: Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.

Gene: WARS

Molecular Weight: 25 kDa

Gene ID: 7453

UniProt: P23381