WSB1 antibody (Internal Region)

Catalog No. ABIN6266053

The Rabbit Polyclonal anti-WSB1 antibody (ABIN6266053) specifically detects WSB1 in WB, IHC, IF and ICC. The antibody is reactive with Human and Mouse samples.

Quick Overview for WSB1 antibody (Internal Region) (ABIN6266053)

Target: WSB1 (WD Repeat and SOCS Box Containing 1 (WSB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WSB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-WSB1 Antibody

Binding Specificity: Internal Region

Purpose: WSB1 Antibody

Specificity: WSB1 Antibody detects endogenous levels of total WSB1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WSB1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for WSB1

Target: WSB1 (WD Repeat and SOCS Box Containing 1 (WSB1))

Alternative Name: WSB1

Background:

Description: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.

Gene: WSB1

Molecular Weight: 56 kDa

Gene ID: 26118

UniProt: Q9Y6I7