YEATS2 antibody (Internal Region)

Catalog No. ABIN6266078

This Rabbit Polyclonal antibody specifically detects YEATS2 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for YEATS2 antibody (Internal Region) (ABIN6266078)

Target: YEATS2 (YEATS Domain Containing 2 (YEATS2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YEATS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-YEATS2 Antibody

Binding Specificity: Internal Region

Specificity: YEATS2 Antibody detects endogenous levels of total YEATS2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human YEATS2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for YEATS2

Target: YEATS2 (YEATS Domain Containing 2 (YEATS2))

Alternative Name: YEATS2

Background:

Description: Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr) (PubMed:27103431). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (PubMed:27103431).

Gene: YEATS2

Molecular Weight: 150kDa

Gene ID: 55689

UniProt: Q9ULM3