Lamin B1 antibody

Catalog No. ABIN6268707

There are 2+ publications for this product available. The Rabbit Polyclonal anti-Lamin B1 antibody is suitable to detect Lamin B1 in samples from Human, Mouse, Rat, Monkey and Fish. It has been validated for WB, IHC, ICC and IF.

Quick Overview for Lamin B1 antibody (ABIN6268707)

Target: Lamin B1 (LMNB1)

Reactivity: Human, Mouse, Rat, Monkey, Fish

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Lamin B1 Antibody

Purpose: Lamin B1 Antibody

Specificity: Lamin B Antibody detects endogenous levels of total Lamin B

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Lamin B1.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

References for anti-Lamin B1 antibody (ABIN6268707)

Zheng, Feng, Jiang, Wu, Tang, Kuang, Zeng, Zhou, Liu: "Selenium deficiency impaired immune function of the immune organs in young grass carp (Ctenopharyngodon idella)." in: Fish & shellfish immunology, Vol. 77, pp. 53-70, (2018) (PubMed).

Yu, Bai, Liu, Yang, Yuan, Zou, Qu, Tian, Song, Zhang, Li, Liu, Wang, Ren, Li: "Fibroblast growth factor (FGF21) protects mouse liver against D-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways." in: Molecular and cellular biochemistry, Vol. 403, Issue 1-2, pp. 287-99, (2015) (PubMed).

Target Details for Lamin B1

Target: Lamin B1 (LMNB1)

Alternative Name: Lamin B1

Background:

Description: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

Gene: LMNB1

Molecular Weight: 66 kDa

Gene ID: 4001

UniProt: P20700

Pathways: Apoptosis, Caspase Cascade in Apoptosis